Fish Oil: Benefits, Uses, Side Effects, and More

Fish Oil: Benefits, Uses, Side Effects, and More

Greentech Blog 22/03/2025

Fish oil has become widely recognized as a popular dietary supplement because it is packed with omega-3 fatty acids. These essential nutrients play a critical role in maintaining overall health, from supporting brain function to reducing inflammation. In this article, we’ll explore the benefits of fish oil, its potential side effects, and its various uses, while addressing common questions like “fish oil is for what?”. Whether you’re curious about fish oil price or its role in specific health conditions, this guide has you covered.

What is Fish Oil?

Fish oil is derived from the tissues of fatty fish like salmon, mackerel, sardines, and trout. It is a rich source of omega-3 fatty acids, specifically docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA). 

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These fatty acids support numerous bodily functions, including brain health, heart function, and inflammation regulation.

The body cannot produce omega-3s on its own, so they need to be sourced from food or supplements. Some plant-based sources, such as flaxseeds and walnuts, provide alpha-linolenic acid (ALA), which the body can partially convert into DHA and EPA. However, this conversion process is not very efficient, making direct consumption of DHA and EPA through fish or Omega-3 supplements a preferred option for many.

Fish Oil Benefits

Fish-derived oil is commonly taken for its anti-inflammatory and cardiovascular benefits. These are the key benefits worth noting:

1. Heart Health

  • Regular consumption of fish extract from dietary sources is linked to a lower risk of heart disease.
  • It helps reduce triglyceride levels, a type of fat in the blood that increases heart disease risk.
  • Some studies indicate that Omega-3 supplements may lower blood pressure, particularly in individuals with moderate to severe hypertension.
  • There is mixed evidence regarding the role of fish extract in reducing bad cholesterol (LDL). While it can lower triglycerides, it may slightly increase LDL levels.
  • Omega-3s may also contribute to improved blood vessel function and reduced risk of blood clot formation, which can help prevent stroke and heart attacks.

2. Joint and Bone Health

  • This nutritional oil is often recommended for people with rheumatoid arthritis. It may help reduce joint pain, stiffness, and the need for anti-inflammatory medications.
  • Some studies suggest that omega-3s contribute to bone strength by reducing bone loss, particularly in aging individuals.
  • There is emerging evidence that this oil could help alleviate symptoms of osteoarthritis by reducing joint degeneration and inflammation.

3. Brain Performance and Mental Stability

  • DHA plays a crucial role in the brain's structure and function. Fish-based oil is believed to support cognitive function and memory.
  • Some research indicates that omega-3s may help manage symptoms of depression and anxiety, though findings are inconclusive.
  • People with bipolar disorder should consult a healthcare provider before taking it, as it may exacerbate certain symptoms.
  • Omega-3 fatty acids may also play a role in neuroprotection and could help reduce the risk of neurodegenerative diseases such as Alzheimer's.

4. Fetal Development and Health

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Omega-3s are vital for the development of a baby's brain and eyes during pregnancy.

  • Pregnant and breastfeeding women can benefit from this health oil, but should avoid fish high in mercury, such as swordfish and king mackerel.
  • Some studies suggest that adequate omega-3 intake during pregnancy may help lower the risk of preterm birth and improve overall fetal health outcomes.

5. Weight Management

  • High-dose Omega-3 supplements may help slow weight loss in individuals with cancer-related cachexia (wasting syndrome).
  • However, there is no conclusive evidence that fish-based oil promotes weight loss in healthy individuals.
  • Some studies suggest that fish-based oil may help regulate metabolism and fat storage, which could have indirect benefits for maintaining a healthy weight.

6. Liver Health

  • fish-based oil may help reduce fat accumulation in the liver, making it beneficial for individuals with nonalcoholic fatty liver disease (NAFLD).
  • Omega-3s could also aid in reducing liver inflammation and improving overall liver function.

7. Eye Health

  • Omega-3s contribute to eye health, but there is no strong evidence that fish-based oil supplements prevent age-related macular degeneration (AMD).
  • Some studies suggest that omega-3s may help reduce symptoms of dry eye syndrome and improve overall eye lubrication.

Fish Oil Uses

This oil is used for a variety of health conditions, with varying levels of effectiveness:

Effective For

  • High triglycerides: Prescription fish-based oil drugs like Lovaza and Epanova are highly effective in reducing very high triglyceride levels.
  • Rheumatoid arthritis: Omega-3 supplements can modestly reduce pain and inflammation.

Possibly Effective For

  • High blood pressure: Fish-derived oil may slightly lower blood pressure in individuals with hypertension.
  • Kidney health: It may help protect against kidney damage caused by certain medications.
  • Menstrual cramps: Fish-based oil, especially when combined with vitamin B12 or E, can reduce pain and the need for painkillers.

Possibly Ineffective For

  • Diabetes: This oil does not lower blood sugar levels or reduce the risk of diabetes-related complications.
  • Eczema: While eating fish may reduce the risk of eczema in children, fish-based oil supplements do not appear to help.
  • Memory and cognitive function: Fish-derived oil does not significantly improve memory or thinking skills in most individuals.

Risks of High Doses

The recommended dosage of fish-derived oil depends on the individual’s health needs:

  • To support overall health, a daily intake of 250–500 mg of EPA and DHA combined is recommended.
  • For high triglycerides: 2–4 grams daily, as prescribed by a healthcare provider.
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Always consult a doctor before starting Omega-3 supplements, especially if you have underlying health conditions or are taking other medications.

Taking more than 3 grams per day of fish-derived oil may increase the risk of:

  • Excessive bleeding
  • Weakened immune response
  • Elevated LDL cholesterol
  • Abnormal heart rhythms in people who have defibrillator devices.
  • More frequent occurrences of digestive disturbances

Fish Oil Side Effects

When taken in recommended doses (up to 3 grams per day), fish-derived oil is generally considered safe. That said, a few individuals might notice minor side effects, such as:

  • Fishy aftertaste
  • Bad breath
  • Heartburn
  • Nausea and diarrhea
  • Rash

Who Should Avoid Fish Oil?

While it is safe for most people, certain individuals should exercise caution:

  • Pregnant or breastfeeding women: Fish-derived oil is often recommended during pregnancy due to its high DHA content, which supports fetal brain development. However, pregnant women should avoid fish high in mercury, such as swordfish and king mackerel, and limit their intake to 12 ounces of low-mercury fish per week.
  • People with seafood allergies: Some individuals allergic to fish may also react to fish-based oil supplements.
  • Those on blood-thinning medications: It can increase the risk of bleeding.

Fish Oil Interactions

Fish oil supplements may interact with certain medications and should be used with caution in specific conditions:

Moderate Interactions

  • Medications that reduce blood clotting (e.g., Warfarin, aspirin). – Fish-based oil may enhance the blood-thinning effects, increasing the risk of bleeding.
  • High blood pressure medications – This nutrition oil may further lower blood pressure, leading to hypotension.
  • Contraceptives – Some birth control pills may reduce the triglyceride-lowering effect of fish-derived oil.
  • Orlistat (weight loss drug) – May reduce the absorption of its fatty acids.
  • Pharmaceuticals that reduce immune activity (e.g., Cyclosporine, Tacrolimus) – This oil may increase drug levels in the body, intensifying effects and side effects.

Minor Interactions

  • Antiplatelet drugs – It may increase bleeding risk.
  • Vitamin E – It  may reduce vitamin E levels in the body.

Fish Oil Price and Availability

The price of Omega-3 supplements varies based on brand, quality, and dosage. Prescription-strength fish-derived oil tends to be more expensive than over-the-counter options. On average:

  • Standard fish-derived oil capsules: $10–$30 per bottle (100–200 capsules).
  • High-potency or pharmaceutical-grade fish-derived oil: $40–$100 per bottle.
  • Liquid fish-derived oil: $20–$50 per bottle, often flavored to improve palatability.

Fish Oil: Is It Right for You?

Fish oil is a versatile supplement with numerous benefits, particularly for heart health, inflammation, and brain function. However, it’s not a cure-all, and its effectiveness varies depending on the condition. Although it is considered safe for most, it’s crucial to understand possible side effects and how it may interact with other drugs

If you’re considering fish oil, consult your healthcare provider to determine the right dosage and form for your needs. Whether you’re looking to improve your heart health, reduce inflammation, or support brain function, it may be a valuable addition to your wellness routine.

By understanding the benefits, side effects, and uses of fish oil, you can make an informed decision about whether it’s right for you. Remember, while supplements can be helpful, they should complement a balanced diet and healthy lifestyle.

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